Mères célibataires par choix ? Une enquête par questionnaire auprès de femmes recourant à la PMA pour avoir un enfant dans un projet de monoparentalité

Séminaire "Quantitativisme réflexif", ENS Paris-Saclay, Feb 2023, Gif Sur Yvette, France

Microscopic and chemical characterization of seashell co-products for valorization in cementitious materials

40ème Rencontres Universitaires de Génie Civil, May 2022, Lille, France

In order to reduce the environmental impact of the construction sector, research has been led to use seashell co-products in cementitious materials, showing they could bring better durability properties...

Therapeutic Potential of MF-TTZ-MMAE, a Site-Specifically Conjugated Antibody-Drug Conjugate, for the Treatment of HER2-Overexpressing Breast Cancer

Bioconjugate Chemistry, 2022, 33 (2), pp.418-426. ⟨10.1021/acs.bioconjchem.2c00015⟩

With three clinically approved antibody-drug conjugates targeting HER2, this target is clearly identified to be of interest in oncology. Moreover, the advent of new bioconjugation technologies producing...

Antibody–Drug Conjugates as an Emerging Therapy in Oncodermatology

Cancers, 2022, 14 (3), 19 p. ⟨10.3390/cancers14030778⟩

Antibody–drug conjugates (ADCs) are an emerging class of therapeutics, with twelve FDA- and EMA-approved drugs for hematological and solid cancers. Such drugs consist in a monoclonal antibody linked to...

Akkermansia muciniphila upregulates genes involved in maintaining the intestinal barrier function via ADP-heptose-dependent activation of the ALPK1/TIFA pathway

Gut microbes, 2022, 14 (1), pp.2110639. ⟨10.1080/19490976.2022.2110639⟩

The commensal bacteria that make up the gut microbiota impact the health of their host on multiple levels. In particular, the interactions taking place between the microbe-associated molecule patterns...

2022-08-28

Microstructure and durability properties of concretes based on oyster shell co-products

75th Rilem Annual Week and International Conference on Advances in Sustainable Construction Materials and Structures, Aug 2021, Merida, Mexico

Alcohol consumption among French physicians: A cross-sectional study

Drug and Alcohol Dependence, 2021, 218, pp.108356. ⟨10.1016/j.drugalcdep.2020.108356⟩

Background: Data regarding French physicians' alcohol behaviours are scarce and most studies address this issue within the population of either medical students or residents. We aim to describe and assess...

Short Chain Fatty Acids – mechanisms and functional importance in the gut

Proceedings of the Nutrition Society, 2021, 80 (1), pp. 37-49. ⟨10.1017/S0029665120006916⟩

In recent years, the importance of the gut microbiota in human health has been revealed and many publications have highlighted its role as a key component of human physiology. Owing to the use of modern...

Fusobacterium nucleatum Extracellular Vesicles Modulate Gut Epithelial Cell Innate Immunity via FomA and TLR2

Frontiers in Immunology, 2020, 11, ⟨10.3389/fimmu.2020.583644⟩

Extracellular vesicles (EVs) derived from the gut microbiota are largely uncharacterized and their impacts on host intestinal physiology remain unresolved. Here, we isolated EVs from F. nucleatum for ...

Adhésion et critique à l’épreuve de l’enquête

Séminaire transversal du Centre Max Weber, Jan 2020, Lyon, France

In Vitro Characterization and Stability Profiles of Antibody–Fluorophore Conjugates Derived from Interchain Cysteine Cross-Linking or Lysine Bioconjugation

Pharmaceuticals, 2019, 12 (4), pp.176. ⟨10.3390/ph12040176⟩

Fluorescent labelling of monoclonal antibodies (mAbs) is classically performed by chemical bioconjugation methods. The most frequent labelling technique to generate antibody-fluorophore conjugates (AFCs...

Site-specific conjugation of auristatins onto engineered antibody fragments to target her2-positive breast cancer in vitro

32ème Colloque Biotechnocentre, Oct 2019, Seillac, France. , 85 p., 2019

The combination of a highly potent cytotoxic agent (drug) with a specific therapeutic monoclonal antibody (mAb) via a suitably constructed spacer arm (linker) (Figure 1) appear to be an ideal embodiment...

Méthodologie utilisant une carte des végétations (CarHAB) en vue de préciser les informations pédologiques de la carte des pédopaysages (RRP) à l’échelle du PNR Livradois-Forez

Sciences de la Terre. 2019

Ce rapport de stage traite des relations existant entre le sol et la végétation. Il a été rédigé dans le cadre d’un stage permettant le début d’un partenariat entre le Conservatoire Botanique national...

Identification of the novel role of butyrate as AhR ligand in human intestinal epithelial cells

Scientific Reports, 2019, 9 (1), pp.643. ⟨10.1038/s41598-018-37019-2⟩

The ligand activated transcription factor, aryl hydrocarbon receptor (AhR) emerged as a critical regulator of immune and metabolic processes in the gastrointestinal tract. In the gut, a main source of...

2019-01-24

Butyrate produced by commensal bacteria down-regulates indolamine 2, 3-dioxygenase 1 (IDO-1) expression via a dual mechanism in human intestinal epithelial cells

Frontiers in Immunology, 2018, 9, ⟨10.3389/fimmu.2018.02838⟩

Commensal bacteria are crucial for the development and maintenance of a healthy immune system therefore contributing to the global wellbeing of their host. A wide variety of metabolites produced by commensal...